Our latest publication, in collaboration with Yamuna Krishnan in Chicago, is out today in Science! In this work, we show that ATP can act as a biological hydrotrope, keeping proteins soluble. Hydrotropes are amphiphilic small molecules that solubilize hydrophobic molecules in aqueous solutions. While ATP is most commonly known as the energy source for cells, there […]
Category Archives: Video
ATP as a biological hydrotrope — congratulations to Avinash, Liliana, and colleagues on their paper in Science, in collaboration with Yamuna Krishnan from UChicago!
Also posted in Publication
Comments closed
New! Video abstract for “Amyloid-like self-assembly of a cellular compartment”
Watch the video abstract for Boke et al 2016, “Amyloid-like self-assembly of a cellular compartment,” and see the full post about it on the Science Sketches website!
Posted in Video
Comments closed
Video: Interview with Tony about phase transitions and disease
Watch a video of Tony explaining phase transitions and disease on the new website “Latest Thinking,” which is a video collection of researchers explaining their latest breakthroughs. Be sure to also check out the videos of Tony answering other short questions in the “Beyond” section just below the main video.
Also posted in Tony
Comments closed
Congratulations to Oliver, Jeff, and colleagues on their paper & video abstract in Biology Open, investigating regulation of centrosome assembly
In new work published this month in Biology Open, Oliver Wueseke, David Zwicker, Jeff Woodruff, and colleagues show that PKL-1 phosphorylation of the centrosome scaffold protein SPD-5 is a key regulatory step which determines centrosome size and density. Importantly, they show that this step is not necessary for proper maintenance or function of the centrosome. […]
Also posted in Publication
Comments closed
Congratulations to Shamba on his paper in Cell on the positioning of liquid-like compartments through an RNA competition mechanism. Plus – video abstract!
In a collaboration with the group of Frank Jülicher at the MPI-PKS, Shamba Saha and colleagues have discovered that an RNA-competition mechanism is at the heart of correct P granule positioning in C. elegans. P granules are liquid-like compartments that segregate to the posterior end of the one-cell embryo before cell division. Previous work in […]
Also posted in Publication
Comments closed
New video on iBiology: Encouraging Innovation
In a new talk filmed for iBiology.org, Tony makes the case that funding young investigators is critical to encouraging scientific innovation. Tony discusses the European models of EMBL and the ERC as examples of successful way to separate the funding of junior and senior scientists, thereby giving young investigators more freedom to innovate. As evidence for […]
Also posted in Tony
Comments closed
Congratulations to Mark on his paper in Biology Open examining the genetic link between temperature and fertility in nematodes. Plus – video abstract!
Congratulations to Mark Leaver on his publication in Biology Open, which is open access and available now online! Click here for the full text. And watch Mark’s 2 minute video abstract below! Leaver M, Kienle S, Begasse ML, Sommer RJ, Hyman AA. A locus in Pristionchus pacificus that is responsible for the ability to give rise to fertile offspring at higher […]
Also posted in Publication
Comments closed
Biscuit, the group leader
Here’s a short, funny clip that was filmed as part of a movie for the birthday celebration and symposium of MPI-CBG Director Eli Knust. If only Eli had let Tony make Biscuit a new group leader when she was the managing director!
Congratulations to Avinash Patel and Hyun Kate Lee on our latest publication in Cell, linking liquid-to-solid phase transition in cells to neurodegenerative disease. Check out the paper and video abstract!
Congratulations to Avinash, Kate, and colleagues for their recent publication in Cell! This work, a close collaboration between our lab and Simon Alberti’s lab, focuses on a protein called FUS, which is implicated in ALS (also known as Lou Gehrig’s disease). By using in vitro and in vivo studies, they show that FUS normally forms liquid compartments. However, when these compartments are “aged” in vitro, they […]
Also posted in Publication
Comments closed
New Two Minute Talk! Watch Maria Begasse’s video abstract for her new paper
The latest addition to our “Two Minute Talk” series is also our very first video abstract for a Hyman Lab publication (Begasse et al, 2015). Check it out below! And don’t miss Mark’s Two Minute Talk for more information on the current follow-up work in the lab related to Maria’s paper. Written and narrated by […]
Also posted in fun, Publication
Comments closed
