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Kazuhisa Kinoshita

Kazuhisa Kinoshita
Senior Research Scientist, RIKEN Advanced Science Institute

Hyman Lab postdoc from 1998-2006

Hyman Lab publications:
Tournebize, R., Popov, A., Kinoshita, K., Ashford, A.J., Rybina, S., Pozniakovsky, A., Mayer, T.U., Walczak, C.E., Karsenti, E. and Hyman, A.A. (2000) Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts. Nature Cell Biology 2: 13-19

Zumbrunn J, Kinoshita K, Hyman AA, Nathke IS (2001). Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3beta phosphorylation. Curr Biol. 11(1): 44-9.

Popov AV, Pozniakovsky A, Arnal I, Antony C, Ashford AJ, Kinoshita K, Tournebize R, Hyman AA, Karsenti E. (2001) XMAP215 regulates microtubule dynamics through two distinct domains. EMBO J. 20(3): 397-410.

Kazuhisa Kinoshita, Isabelle Arnal, Arshad Desai, David N. Drechsel, and Anthony A. Hyman (2001) Reconstitution of Physiological Microtubule Dynamics Using Purified Components. Science 294: 1340-1343.

Kinoshita K, Habermann B and Hyman A (2002) XMAP 215: a key component of the dynamic microtubule cytoskeleton. Trends in Cell Biology 12(6): 267-273

Noetzel TL, Drechsel DN, Hyman AA, Kinoshita K. (2005) A comparison of the ability of XMAP215 and tau to inhibit the microtubule destabilizing activity of XKCM1. Philos Trans R Soc Lond B Biol Sci. 360(1455): 591-4.

Ozlu N, Srayko M, Kinoshita K, Habermann B, O’toole ET, Muller-Reichert T, Schmalz N, Desai A, Hyman AA. (2005) An Essential Function of the C. elegans Ortholog of TPX2 Is to Localize Activated Aurora A Kinase to Mitotic Spindles. Dev Cell. 9(2): 237-48.

Barros TP, Kinoshita K, Hyman AA, Raff JW. (2005) Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules. J Cell Biol. 170(7): 1039-46.

Kinoshita K, Noetzel TL, Pelletier L, Mechtler K, Drechsel DN, Schwager A, Lee M, Raff JW, Hyman AA. (2005) Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. J Cell Biol. 170(7): 1047-55.

Kinoshita K, Noetzel TL, Arnal I, Drechsel DN, Hyman AA. (2006) Global and local control of microtubule destabilization promoted by a catastrophe kinesin MCAK/XKCM1. J Muscle Res Cell Motil. 27(2): 107-14.

Brouhard GJ, Stear JH, Noetzel TL, Al-Bassam J, Kinoshita K, Harrison SC, Howard J, Hyman AA (2008). XMAP215 is a processive microtubule polymerase Cell 132(1): 79-88

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