Selected Publications

Funding Innovative Science.
Science 2013 Jan. 11; Vol. 339 no. 6116 p. 119. [Article]

In Retrospect: The Origin of Life.
Nature 2012 [PDF]
Hyman AA, Brangwynne CP

ASCB Profile
ASCB Newsletter. 2012 Nov. [PDF]

The new cell biology: Beyond HeLa cells
Nature. 2011 Nov 30;480(7375):34. [PubMed]

Whither systems biology
Phil. Trans. R. Soc. B. 2011 366, 3635-3637. [PDF]

Beyond Stereospecificity: Liquids and Mesoscale Organization of Cytoplasm
Dev Cell. 2011 Jul 19;21(1):14-6. [PDF]

Q & A – Tony Hyman
Curr Biol. 2011 Apr 12;21(7):R240-2. [PDF]

Automating Cell Biology
ASCB Newsletter. 2011 Mar. [PDF]

European vs. U.S. Careers
ASCB Newsletter. 2010 Oct. [PDF]

Anthony Hyman: From unlikely scientist to Royal Society Fellow
J Cell Biol. 2007 Dec 31;179(7):1330-1. [PDF]

A pipeline for Europe
Nature. 2007 Sep 13;449(7159):256. [PDF]

Boveri revisited
EMBO J. 2005 Mar 23;24(6):1104-10. [PDF]

Goehring NW, Hyman AA.  Organelle Growth Control through Limiting Pools of Cytoplasmic Components.
Curr Biol. 2012 May 8;22(9):R330-9.  [PubMed]

Reber S, Hyman AA. Samurai sword sets spindle size.
Cell. 2011 Dec 9;147(6):1224-5. [PubMed]

Howard J, Hyman AA. Growth, fluctuation and switching at microtubule plus ends.
Nat Rev Mol Cell Biol. 2009 Jun 10. [PDF]

Cowan CR, Hyman AA.  Acto-myosin reorganization and PAR polarity in C. elegans.
Development. 2007 Mar;134(6):1035-43. [PDF]

Howard J, Hyman AA.  Microtubule polymerases and depolymerases.
Curr Opin Cell Biol. 2007 Feb;19(1):31-5. [PDF]

Oegema K, Hyman AA. Cell division.
WormBook. 2006 Jan 19:1-40.[WormBook]

Kinoshita K, Noetzel TL, Arnal I, Drechsel DN, Hyman AA.  Global and local control of microtubule destabilization promoted by a catastrophe kinesin MCAK/XKCM1.
J Muscle Res Cell Motil.  2006;27(2):107-14. [PDF]

Hyman AA, Howard J. Cell structure and dynamics. 
Curr Opin Cell Biol. 2005 Feb;17(1):1-2. [PDF]

Cowan CR, Hyman AA.   Asymmetric cell division in C. elegans: cortical polarity and spindle positioning.
Annu Rev Cell Dev Biol. 2004;20:427-53. [PDF]

Howard J and Hyman AA. Dynamics and mechanics of the microtubule plus end.
Nature. 2003; 422 (6933): 753-8. [PDF]

Wittmann T, Hyman AA, Desai A.  The spindle: a dynamic assembly of microtubules and motors.
Nat Cell Biol. 2001 E28-34.[PDF]

Hyman AA. Centrosomes: Sic transit gloria centri
Curr Biol. 2000 Apr 6;10(7):R276-8.  [Article]

Scolz M, Widlund PO, Piazza S, Bublik DR, Reber S, Peche LY, Ciani Y, Hubner N, Isokane M, Monte M, Ellenberg J, Hyman AA, Schneider C, Bird AW.  GTSE1 Is a Microtubule Plus-End Tracking Protein That Regulates EB1-Dependent Cell Migration.
PLoS One 2012 Dec. 20 [Epub ahead of print][PubMed]

Widlund PO, Podolski M, Reber S, Alper J, Storch M, Hyman AA, Howard J, and Drechsel DN.  One-step purification of assembly competent tubulin from diverse eukaryotic sources.
Mol Biol Cell. 2012 Nov;23(22):4393-401. (Epub 2012 Sep 19) [PubMed]

Weber B, Greenan G, Prohaska S, Baum D, Hege HC, Müller-Reichert T, Hyman AA, Verbavatz JM. Automated tracing of microtubules in electron tomograms of plastic embedded samples of Caenorhabditis elegans embryos.
J Struct Biol. 2012; 178(2): 129-138. [PubMed]

Widlund PO, Stear JH, Pozniakovsky A, Zanic M, Reber S, Brouhard GJ, Hyman AA, Howard J.  XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region.
Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2741-6. (Epub 2011 Jan 31) [PubMed]

Zanic M, Stear JH, Hyman AA, Howard J. EB1 recognizes the nucleotide state of tubulin in the microtubule lattice.
PLoS One. 2009 Oct 23;4(10):e7585.[PDF]

Brouhard GJ, Stear JH, Noetzel TL, Al-Bassam J, Kinoshita K, Harrison SC, Howard J, Hyman AA. XMAP215 is a processive microtubule polymerase.
Cell 2008 Jan 11;132(1):79-88.[PDF]

Elie-Caille C, Severin F, Helenius J, Howard J, Muller DJ, Hyman AA.  Straight GDP-tubulin protofilaments form in the presence of taxol.
Curr Biol. 2007 Oct 23;17(20):1765-70.[PDF]

Al-Bassam J, Larsen NA, Hyman AA, Harrison SC. Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding.
Structure. 2007 Mar;15(3):355-62.[PDF]

Al-Bassam J, van Breugel M, Harrison SC, Hyman AA. Stu2p binds tubulin and undergoes an open-to-closed conformational change.
J Cell Biol. 2006 Mar 27;172(7):1009-22.[PDF]

Barros TP, Kinoshita K, Hyman AA, Raff JW. Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules.
J Cell Biol. 2005 Sep 26;170(7):1039-46.[PDF]

Srayko M, Kaya A, Stamford J, Hyman AA. Identification and Characterization of Factors Required for Microtubule Growth and Nucleation in the Early C. elegans Embryo.
Dev Cell. 2005 Aug;9(2):223-36.[PDF]

Noetzel TL, Drechsel DN, Hyman AA, Kinoshita K. A comparison of the ability of XMAP215 and tau to inhibit the microtubule destabilizing activity of XKCM1.
Philos Trans R Soc Lond B Biol Sci. 2005 Mar 29;360(1455):591-4.[PDF]

Van Breugel M, Hyman AA, Drechsel D. Stu2p, the budding yeast member of the conserved Dis1/XMAP215 family of microtubule-associated proteins is a plus end-binding microtubule destabilizer.
J Cell Biol. 2003 April 28; 161 (2): 1-13.[PDF]

Srayko M, Quintin S, Schwager A, Hyman AA. Caenorhabditis elegans TAC-1 and ZYG-9 form a complex that is essential for long astral and spindle microtubules.
Curr Biol. 2003 Sep 2;13(17):1506-11.[PDF]

Kinoshita K, Arnal I, Desai A, Drechsel DN, Hyman AA. Reconstitution of Physiological Microtubule Dynamics Using Purified Components.
Science. 2001; 294: 1340-1343.[PDF]

Arnal I, Karsenti E, Hyman AA. Structural Transitions at microtubule ends correlate with their dynamic properties in Xenopus egg extracts.
J Cell Biol. 2000; 149: 767-774.[PDF]

Decker M, Jaensch S, Pozniakovsky A, Zinke A, O’Connell KF, Zachariae W, Myers E, Hyman AA.  Limiting Amounts of Centrosome Material Set Centrosome Size in C. elegans Embryos.
Curr Biol. 2011 Aug 9;21(15):1259-67. (Epub 2011 Jul 28)  [PubMed]

Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA, Andersen JS.  Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
EMBO J. 2011 Apr 20;30(8):1520-35. (Epub 2011 Mar 11)  [PubMed]

Greenan G, Brangwynne CP, Jaensch S, Gharakhani J, Jülicher F, Hyman AA.  Centrosome size sets mitotic spindle length in Caenorhabditis elegans embryos.
Curr Biol. 2010 Feb 23;20(4):353-8. (Epub 2010 Feb 4) [PubMed]

Jaensch S, Decker M, Hyman AA, Myers EW.  Automated tracking and analysis of centrosomes in early Caenorhabditis elegans embryos.
Bioinformatics. 2010 Jun 15;26(12):i13-20.  [PubMed]

Lawo S, Bashkurov M, Mullin M, Ferreria MG, Kittler R, Habermann B, Tagliaferro A, Poser I, Hutchins JR, Hegemann B, Pinchev D, Buchholz F, Peters JM, Hyman AA, Gingras AC, Pelletier L.  HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.
Curr Biol. 2009 May 26;19(10):816-26. [PubMed]

Boxem M, Maliga Z, Klitgord N, Li N, Lemmens I, Mana M, de Lichtervelde L, Mul JD, van de Peut D, Devos M, Simonis N, Yildirim MA, Cokol M, Kao HL, de Smet AS, Wang H, Schlaitz AL, Hao T, Milstein S, Fan C, Tipsword M, Drew K, Galli M, Rhrissorrakrai K, Drechsel D, Koller D, Roth FP, Iakoucheva LM, Dunker AK, Bonneau R, Gunsalus KC, Hill DE, Piano F, Tavernier J, van den Heuvel S, Hyman AA, Vidal M.  A protein domain-based interactome network for C. elegans early embryogenesis.
Cell. 2008 Aug 8;134(3):534-45.  [PDF]

Zhu F, Lawo S, Bird A, Pinchev D, Ralph A, Richter C, Müller-Reichert T, Kittler R, Hyman AA, Pelletier L.  The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis.
Curr Biol. 2008 Jan 22;18(2):136-41.  [PDF]

Schlaitz AL, Srayko M, Dammermann A, Quintin S, Wielsch N, MacLeod I, de Robillard Q, Zinke A, Yates III JR, Müller-Reichert T, Shevchenko A, Oegema K, Hyman AA.   The C. elegans RSA Complex Localizes Protein Phosphatase 2A to Centrosomes and Regulates Mitotic Spindle Assembly.
Cell 2007, January 12; 128(1):115-127.  [Article]

Pelletier L, O’Toole E, Schwager A, Hyman AA, Müller-Reichert T.   Centriole assembly in Caenorhabditis elegans.
Nature. 2006 Nov 30;444(7119):619-23.  [PDF]

Kinoshita K, Noetzel TL, Pelletier L, Mechtler K, Drechsel DN, Schwager A, Lee M, Raff JW, Hyman AA.   Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. 
J Cell Biol. 2005 Sep 26;170(7):1047-55. [PDF]

Ozlu N, Srayko M, Kinoshita K, Habermann B, O’toole ET, Muller-Reichert T, Schmalz N, Desai A, Hyman AA.   An Essential Function of the C. elegans Ortholog of TPX2 Is to Localize Activated Aurora A Kinase to Mitotic Spindles.
Dev Cell. 2005 Aug;9(2):237-48.  [PDF]

Pelletier L, Ozlu N, Hannak E, Cowan C, Habermann B, Ruer M, Muller-Reichert T, Hyman AA.   The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication.
Curr Biol. 2004 May 25;14(10):863-73.  [PDF]

Desai A, Rybina S, Muller-Reichert T, Shevchenko A, Shevchenko A, Hyman AA, Oegema K.  KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans.
Genes Dev. 2003 Oct 1; 17(19):2421-35.  [PDF]

Kirkham M, Mueller-Reichert T, Oegema K, Grill S, Hyman AA.  SAS-4 is a C. elegans Centriolar Protein that Controls Centrosome Size.
Cell. 2003 Feb 21; 112 (575-587).  [PDF]

Hannak E, Oegema K, Kirkham M, Gonczy P, Habermann B, Hyman AA.  The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent.
J Cell Biol. 2002 May 13; 157 (4): 591-602.  [PDF]

Hannak E, Kirkham M, Hyman AA and Oegema K.   Aurora-A kinase is required for centrosome maturation in C. elegans.
J Cell Biol. 2001 155 (7) 1109-1115.  [PDF]

Hyman AA, Simons K.  Cell Biology. Beyond oil and water–phase transitions in cells.
Science. 2012 Aug 31;337(6098):1047-1049. [PubMed]

Hyman AA, Brangwynne, CP.  Beyond Stereospecificity: Liquids and Mesoscale Organization of Cytoplasm
Dev Cell. 2011 Jul 19;21(1):14-6. [PDF]

Brangwynne CP, Mitchison TJ, Hyman AA. Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes.
Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4334-9. (Epub 2011 Feb 28) [PubMed]

Brangwynne CP, Eckmann CR, Courson DS, Rybarska A, Hoege C, Gharakhani J, Jülicher F, Hyman AA.  Germline P granules are liquid droplets that localize by controlled dissolution/condensation.
Science. 2009 Jun 26;324(5935):1729-32.  [PubMed]

Goehring NW, Trong PK, Bois JS, Chowdhury D, Nicola EM, Hyman AA, Grill SW. Polarization of PAR proteins by advective triggering of a pattern-forming system
Science. 2011 Nov 25;334(6059):1137-41.  [PubMed]

Goehring NW, Hoege C, Grill SW, Hyman AA.  PAR proteins diffuse freely across the anterior-posterior boundary in polarized C. elegans embryos.
J Cell Biol. 2011 May 2;193(3):583-94. (Epub 2011 Apr 25)  [PubMed]

Stewart MP, Helenius J, Toyoda Y, Ramanathan SP, Muller DJ, Hyman AA.  Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding.
Nature. 2011 Jan 13;469(7329):226-30. (Epub 2011 Jan 2)  [Article]

Goehring NW, Chowdhury D, Hyman AA, Grill SW.  FRAP Analysis of Membrane-Associated Proteins: Lateral Diffusion and Membrane-Cytoplasmic Exchange.
Biophys J. 2010 Oct 20;99(8):2443-52.  [PubMed]

Redemann S, Pecreaux J, Goehring NW, Khairy K, Stelzer EH, Hyman AA, Howard J.  Membrane Invaginations Reveal Cortical Sites that Pull on Mitotic Spindles in One-Cell C. elegans Embryos.
PLoS One. 2010 Aug 20;5(8).  [Article]

Hoege C, Constantinescu AT, Schwager A, Goehring NW, Kumar P, Hyman AA. LGL can partition the cortex of one-cell Caenorhabditis elegans embryos into two domains.
Curr Biol. 2010 Jul 27;20(14):1296-303. (Epub 2010 Jun 24)  [PubMed]

Petrásek Z, Hoege C, Mashaghi A, Ohrt T, Hyman AA, Schwille P.   Characterization of protein dynamics in asymmetric cell division by scanning fluorescence correlation spectroscopy.
Biophys J. 2008 Dec;95(11):5476-86.  [PubMed]

Pecreaux J, Röper JC, Kruse K, Jülicher F, Hyman AA, Grill SW, Howard J.   Spindle oscillations during asymmetric cell division require a threshold number of active cortical force generators.
Curr Biol. 2006 Nov 7;16(21):2111-22.  [PubMed]

Cowan CR, Hyman AA.  Cyclin E-Cdk2 temporally regulates centrosome assembly and establishment of polarity in Caenorhabditis elegans embryos.
Nat Cell Biol. 2006 Dec;8(12):1441-7.  [PubMed]

Schonegg S and Hyman AA.  CDC-42 and RHO-1 coordinate acto-myosin contractility and PAR protein localization during polarity establishment in C. elegans embryos. 
Development 2006 Sep;133(18):3507-16.  [PubMed]

Bringmann H and Hyman AA. A cytokinesis furrow is positioned by two consecutive signals.
Nature 436, 731-734 (4 August 2005).  [Article]

Cowan CR, Hyman AA.  Centrosomes direct cell polarity independently of microtubule assembly in C. elegans embryos. 
Nature. 2004 Sep 2;431(7004):92-6.  [Article]

Grill SW, Howard J, Schaffer E, Stelzer EH, Hyman AA.  The distribution of active force generators controls mitotic spindle position.
Science 2003 Jul 25; 301 (5632):518-21.  [PubMed]

Grill, S. Gonczy P. Stelzer, E and Hyman AA.  Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo. 
Nature 2001; 409(6820):630-3.  [PubMed]

Jantsch-Plunger V, Gonczy P, Romano A, Schnabel H, Hamill D, Schnabel R, Hyman AA, Glotzer M.   CYK-4: A Rho Family GTPase Activating Protein (GAP) Required for Central Spindle Formation and Cytokinesis.
J. Cell Biol. 2000; 149(7): 1391-1404.  [PubMed]

Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J.   Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes.
Nature. 2010 Apr 1;464(7289):721-7. [PubMed]

Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM.   Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Science. 2010 Apr 30;328(5978):593-9. (Epub 2010 Apr 1) [PubMed]

Kittler R, Pelletier L, Heninger AK, Slabicki M, Theis M, Miroslaw L, Poser I, Lawo S, Grabner H, Kozak K, Wagner J, Surendranath V, Richter C, Bowen W, Jackson AL, Habermann B, Hyman AA, Buchholz F.   Genome-scale RNAi profiling of cell division in human tissue culture cells.
Nat Cell Biol. 2007 Dec;9(12):1401-12.  [PubMed]

Sonnichsen B, Koski LB, Walsh A, Marschall P, Neumann B, Brehm M, Alleaume AM, Artelt J, Bettencourt P, Cassin E, Hewitson M, Holz C, Khan M, Lazik S, Martin C, Nitzsche B, Ruer M, Stamford J, Winzi M, Heinkel R, Roder M, Finell J, Hantsch H, Jones SJ, Jones M, Piano F, Gunsalus KC, Oegema K, Gonczy P, Coulson A, Hyman AA, Echeverri CJ.  Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. 
Nature 2005 Mar 24;434(7032):462-9.  [PubMed]

Gonczy P, Echeverri G, Oegema K, Coulson A, Jones SJ, Copley RR, Duperon J, Oegema J, Brehm M, Cassin E, Hannak E, Kirkham M, Pichler S, Flohrs K, Goessen A, Leidel S, Alleaume AM, Martin C, Ozlu N, Bork P, Hyman AA.   Functional genomic analysis of cell division in C.elegans using RNAi of genes on chromosome III.
Nature 2000 408(6810): 331-6.  [PubMed]

Bird AW, Erler A, Fu J, Hériché JK, Maresca M, Zhang Y, Hyman AA, Stewart AF. High-efficiency counterselection recombineering for site-directed mutagenesis in bacterial artificial chromosomes
Nat Methods. 2011 Dec 4;9(1):103-9.  [PubMed]

Poser I, Sarov M, Hutchins JR, Hériché JK, Toyoda Y, Pozniakovsky A, Weigl D, Nitzsche A, Hegemann B, Bird AW, Pelletier L, Kittler R, Hua S, Naumann R, Augsburg M, Sykora MM, Hofemeister H, Zhang Y, Nasmyth K, White KP, Dietzel S, Mechtler K, Durbin R, Stewart AF, Peters JM, Buchholz F, Hyman AA. BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. 
Nat Methods. 2008 May;5(5):409-15.  [PubMed]

Bird AW, Hyman AA.  Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A.
J Cell Biol. 2008 Jul 28;182(2):289-300. [PubMed]

Sarov M, Schneider S, Pozniakovski A, Roguev A, Ernst S, Zhang Y, Hyman AA, Stewart AF.  A recombineering pipeline for functional genomics applied to Caenorhabditis elegans.
Nat Methods. 2006 Oct;3(10):839-44.  [PubMed]

Kittler R, Pelletier L, Ma C, Poser I, Fischer S, Hyman AA, Buchholz F. RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells. 
Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2396-401.  [PubMed]

Maliga Z, Junqueira M, Toyoda Y, Ettinger A, Mora F, Klemm RW, Vasilj A, Guhr E, Benitez I, Poser I, Simons K, Bonifacio E, Huttner W, Shevchenko A, Hyman AA.   A genomic toolkit to investigate kinesin and myosin motor function in cells.
Nat Cell Biology

Uzunova K, Dye BT, Schutz H, Ladurner R, Petzold G, Toyoda Y, Jarvis MA, Brown NG, Poser I, Novatchkova M, Mechtler K, Hyman AA, Stark H, Schulman BA, Peters JM.   APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex.
Nat Struct Mol Biol. 2012 Sep 24. [PubMed]

Splinter D, Razafsky DS, Schlager MA, Serra-Marques A, Grigoriev I, Demmers J, Keijzer N, Jiang K, Poser I, Hyman AA, Hoogenraad CC, King SJ, Akhmanova A.   BICD2, dynactin and LIS1 cooperate in regulating dynein recruitment to cellular structures.
Mol Biol Cell 2012 Sep 5. [PubMed]

Wurzenberger C, Held M, Lampson MA, Poser I, Hyman AA, Gerlich DW.   Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores.
J Cell Biol. 2012 Jul 16. [PubMed]

Frost A, Elgort MG, Brandman O, Ives C, Collins SR, Miller-Vedam L, Weibezahn J, Hein MY, Poser I, Mann M, Hyman AA, Weissman JS.   Functional Repurposing Revealed by Comparing S. pombe and S. cerevisiae Genetic Interactions.
Cell 2012 Jun 8;149(6):1339-52. [PubMed]

Joseph N, Hutterer A, Poser I, Mishima M.   ARF6 GTPase protects the post-mitotic midbody from 14-3-3-mediated disintegration.
EMBO J. 2012 May 11;31(11):2604-14. [PubMed]

Hegemann B, Hutchins JR, Hudecz O, Novatchkova M, Rameseder J, Sykora MM, Liu S, Mazanek M, Lénárt P, Hériché JK, Poser I, Kraut N, Hyman AA, Yaffe MB, Mechtler K, Peters JM.   Systematic phosphorylation analysis of human mitotic protein complexes.
Sci Signal. 2011 Nov 8;4(198):rs12. [PubMed]

Elefsinioti A, Saraç OS, Hegele A, Plake C, Hubner NC, Poser I, Sarov M, Hyman A, Mann M, Schroeder M, Stelzl U, Beyer A. Large-scale De Novo Prediction of Physical Protein-Protein Association.
Mol Cell Proteomics. 2011 Nov;10(11):M111.010629. [PubMed]

Ettinger AW, Wilsch-Bräuninger M, Marzesco AM, Bickle M, Lohmann A, Maliga Z, Karbanová J, Corbeil D, Hyman AA, Huttner WB.   Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour.
Nat Commun. 2011 Oct 18;2:503. [PubMed]

Ding L, Poser I, Paszkowski-Rogacz M, Buchholz F.   From RNAi Screens to Molecular Function in Embryonic Stem Cells.
Stem Cell Rev. 2011 Apr 28. [PubMed]

Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA, Andersen JS. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
EMBO J. 2011 Apr 20;30(8):1520-35. [PubMed]

Guizetti J, Schermelleh L, Mäntler J, Maar S, Poser I, Leonhardt H, Müller-Reichert T, Gerlich DW.
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments.
Science. 2011 Mar 25;331(6024):1616-20. [Article]

Schnütgen F, Ehrmann F, Poser I, Hubner NC, Hansen J, Floss T, deVries I, Wurst W, Hyman A, Mann M, von Melchner H. Resources for proteomics in mouse embryonic stem cells.
Nat Methods. 2011 Feb;8(2):103-4. [PubMed]

Huranová M, Ivani I, Benda A, Poser I, Brody Y, Hof M, Shav-Tal Y, Neugebauer KM, Stanek D.
The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells.
J Cell Biol. 2010 Oct 4;191(1):75-86. [PubMed]

Schmitz MH, Held M, Janssens V, Hutchins JR, Hudecz O, Ivanova E, Goris J, Trinkle-Mulcahy L, Lamond AI, Poser I, Hyman AA, Mechtler K, Peters JM, Gerlich DW. Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.
Nat Cell Biol. 2010 Sep;12(9):886-93. Epub 2010 Aug 15. [PubMed]

Vermeulen M, Eberl HC, Matarese F, Marks H, Denissov S, Butter F, Lee KK, Olsen JV, Hyman AA, Stunnenberg HG, Mann M. Quantitative Interaction Proteomics and Genome-wide Profiling of Epigenetic Histone Marks and Their Readers.
Cell. 2010 Sep 17;142(6):844-6. [PubMed]

Ankö ML, Morales L, Henry I, Beyer A, Neugebauer KM.  Global analysis reveals SRp20- and SRp75-specific mRNPs in cycling and neural cells.
Nat Struct Mol Biol. 2010 Aug;17(8):962-70. (Epub 2010 Jul 18) [PubMed]

Słabicki M, Theis M, Krastev DB, Samsonov S, Mundwiller E, Junqueira M, Paszkowski-Rogacz M, Teyra J, Heninger AK, Poser I, Prieur F, Truchetto J, Confavreux C, Marelli C, Durr A, Camdessanche JP, Brice A, Shevchenko A, Pisabarro MT, Stevanin G, Buchholz F.  A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia.
PLoS Biol. 2010 Jun 29;8(6). [PubMed]

Spruijt CG, Bartels SJ, Brinkman AB, Tjeertes JV, Poser I, Stunnenberg HG, Vermeulen M.
CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex.
Mol Biosyst. 2010 Sep;6(9):1700-6. (Epub 2010 Jun 4) [PubMed]

Hubner NC, Bird AW, Cox J, Splettstoesser B, Bandilla P, Poser I, Hyman AA, Mann M.   Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions.
J Cell Biol. 2010 May 17;189(4):739-54. [PubMed]

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