Author Archives: hymanlab

The most colorful safety briefing

Our brilliant baker and Masters student Stephen helped make the annual safety briefing much more festive this year. Check out his incredible rainbow cake! 

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New! Video abstract for “Amyloid-like self-assembly of a cellular compartment”

Watch the video abstract for Boke et al 2016, “Amyloid-like self-assembly of a cellular compartment,” and see the full post about it on the Science Sketches website!

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Come see us at ASCB 2016!

The Hyman lab is represented at the 2016 ASCB annual meeting, taking place now in San Francisco. Come see us if you’re here! • Sunday, Dec 4, 12pm-1:30pm: Louise Jawerth presents her poster, “The liquid to gel transition in protein droplets” (poster B1345) • Sunday, Dec 4, 5:20pm-5:35pm: Shamba Saha gives a talk, “An mRNA competition […]

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On Research Funding and the Power of Youth

Read the full essay on the importance of funding young scientists, written for the President’s Column of the October issue of the ASCB newsletter by Tony Hyman, Ashad Desai, and Peter Walter. “On Research Funding and the Power of Youth” – PDF

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Video: Interview with Tony about phase transitions and disease

Watch a video of Tony explaining phase transitions and disease on the new website “Latest Thinking,” which is a video collection of researchers explaining their latest breakthroughs. Be sure to also check out the videos of Tony answering other short questions in the “Beyond” section just below the main video.

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Congratulations to Oliver, Jeff, and colleagues on their paper & video abstract in Biology Open, investigating regulation of centrosome assembly

In new work published this month in Biology Open, Oliver Wueseke, David Zwicker, Jeff Woodruff, and colleagues show that PKL-1 phosphorylation of the centrosome scaffold protein SPD-5 is a key regulatory step which determines centrosome size and density. Importantly, they show that this step is not necessary for proper maintenance or function of the centrosome. […]

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Read our reviews to learn about “Liquid-liquid phase separation in biology”, “Are aberrant phase transitions a driver of cellular aging?”, and “Biomolecular condensates: organizers of cellular biochemistry”

Everything you ever wanted to know about our current understanding of cytoplasmic organization by phase separation, from the physics behind it to the consequences for disease, in one comprehensive review: Liquid-liquid phase separation in biology. Hyman AA, Weber CA, Jülicher F. Annu Rev Cell Dev Biol. 2014 Oct 11;30:39-58. 2016 UPDATE: Also read a new review […]

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Welcome, Ceciel, our newest PhD student!

The Hyman Lab welcomes Ceciel Jegers, our newest PhD student. Ceciel comes to us from the Netherlands, and she will be working on phase transitions in cells and disease.

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Congratulations to Shamba on his paper in Cell on the positioning of liquid-like compartments through an RNA competition mechanism. Plus – video abstract!

In a collaboration with the group of Frank Jülicher at the MPI-PKS, Shamba Saha and colleagues have discovered that an RNA-competition mechanism is at the heart of correct P granule positioning in C. elegans. P granules are liquid-like compartments that segregate to the posterior end of the one-cell embryo before cell division. Previous work in […]

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“No man is an island”: an essay from the archives about the value of collaboration

In 1996, when Tony was a group leader at the EMBL, he wrote an essay for Current Biology entitled “No man is an island” on the importance of long-term collaboration and shared credit in science. The topic is just as relevant today as it was 20 years ago. Maybe it’s time to implement Tony’s two-dimensional […]

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  • Archives


  • Selected Essays

















  • Recent Videos


    An interview with Tony about Phase Transitions and Disease


    Phase separation in cell polarity: Saha et al, Cell 2016


    Encouraging Innovation, iBiology.org


    The genetics linking temperature and fertility in worms: Leaver et al, Biology Open 2016


    Cell PaperFlick on Phase Transitions in Disease


    Check out this playlist to watch all the videos in our "Two Minute Talk" Series


    Ways of Growing, a film created for the MitoSys Project


    What is a Discovery?


    Embryonic Development of C.elegans