Author Archives: hymanlab

New preprint: The centrosome is a selective phase that nucleates microtubules by concentrating tubulin

The Hyman lab is proud to publish preprints, which we post in parallel to journal submission. You can find our latest manuscript on bioRxiv, and we welcome your feedback: The centrosome is a selective phase that nucleates microtubules by concentrating tubulin Jeffrey B Woodruff, Beatriz Ferreira Gomes, Per O Widlund, Julia Mahamid, and Anthony A Hyman

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Photo from lab dinner at ASCB

Here’s a quick photo from last week’s Hyman lab dinner during ASCB 2016 in San Francisco! It was great to see former members like Laurence Pelletier and Garrett Greenan, as well as collaborators Elvan Boke and Marco Hein. See you next year at the joint ASCB/EMBO meeting in Philadelphia!

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Annual Christmas Market outing

After Tony’s annual vision talk at our “Lab Day,” everyone gathered for glühwein and cheer at our traditional trip to the Neumarkt Christmas Market. Happy holidays, everyone!

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The most colorful safety briefing

Our brilliant baker and Masters student Stephen helped make the annual safety briefing much more festive this year. Check out his incredible rainbow cake! 

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New! Video abstract for “Amyloid-like self-assembly of a cellular compartment”

Watch the video abstract for Boke et al 2016, “Amyloid-like self-assembly of a cellular compartment,” and see the full post about it on the Science Sketches website!

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Come see us at ASCB 2016!

The Hyman lab is represented at the 2016 ASCB annual meeting, taking place now in San Francisco. Come see us if you’re here! • Sunday, Dec 4, 12pm-1:30pm: Louise Jawerth presents her poster, “The liquid to gel transition in protein droplets” (poster B1345) • Sunday, Dec 4, 5:20pm-5:35pm: Shamba Saha gives a talk, “An mRNA competition […]

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On Research Funding and the Power of Youth

Read the full essay on the importance of funding young scientists, written for the President’s Column of the October issue of the ASCB newsletter by Tony Hyman, Ashad Desai, and Peter Walter. “On Research Funding and the Power of Youth” – PDF

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Video: Interview with Tony about phase transitions and disease

Watch a video of Tony explaining phase transitions and disease on the new website “Latest Thinking,” which is a video collection of researchers explaining their latest breakthroughs. Be sure to also check out the videos of Tony answering other short questions in the “Beyond” section just below the main video.

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Congratulations to Oliver, Jeff, and colleagues on their paper & video abstract in Biology Open, investigating regulation of centrosome assembly

In new work published this month in Biology Open, Oliver Wueseke, David Zwicker, Jeff Woodruff, and colleagues show that PKL-1 phosphorylation of the centrosome scaffold protein SPD-5 is a key regulatory step which determines centrosome size and density. Importantly, they show that this step is not necessary for proper maintenance or function of the centrosome. […]

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Read our reviews to learn about “Liquid-liquid phase separation in biology”, “Are aberrant phase transitions a driver of cellular aging?”, and “Biomolecular condensates: organizers of cellular biochemistry”

Everything you ever wanted to know about our current understanding of cytoplasmic organization by phase separation, from the physics behind it to the consequences for disease, in one comprehensive review: Liquid-liquid phase separation in biology. Hyman AA, Weber CA, Jülicher F. Annu Rev Cell Dev Biol. 2014 Oct 11;30:39-58. 2016 UPDATE: Also read a new review […]

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    An interview with Tony about Phase Transitions and Disease


    Phase separation in cell polarity: Saha et al, Cell 2016


    Encouraging Innovation, iBiology.org


    The genetics linking temperature and fertility in worms: Leaver et al, Biology Open 2016


    Cell PaperFlick on Phase Transitions in Disease


    Check out this playlist to watch all the videos in our "Two Minute Talk" Series


    Ways of Growing, a film created for the MitoSys Project


    What is a Discovery?


    Embryonic Development of C.elegans