Author Archives: hymanlab

New video abstract! Microtubule nucleation through phase separation

Watch our latest video abstract, created by Amayra Hernández-Vega, describing our recent publication in Cell Reports.

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Celebrating Tony’s Schleiden Medal

The lab went out together to celebrate Tony’s big award! It was a great evening, and you can see a few photos below.     

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Tony in today’s DNN newspaper

The Dresdner Neueste Nachrichten newspaper ran a story today about Tony receiving the Schleiden Medal! You can read the story online here.

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Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase – congratulations to Amayra Hernández-Vega and colleagues on their paper in Cell Reports!

Our latest publication is now out in Cell Reports. In this work, we show that the protein Tau can phase separate into liquid-like droplets in vitro. These droplets can concentrate tubulin, which enables the polymerization of microtubule bundles that deform the droplets into rod-like structures. Read the full paper online (open access full text) and see the […]

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Tony receives Schleiden Medal from German National Academy of Sciences Leopoldina

On behalf of the whole Hyman lab, we want to congratulate Tony on this great honor, which recognizes his achievements and outstanding work in the field of cell biology. You can read the press release on the MPI-CBG website, the text of which is also below. The German National Academy of Sciences Leopoldina presents Anthony Hyman, director […]

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New video abstract! Building synthetic centrosomes.

Watch our latest video abstract, created by Jeff Woodruff, describing our recent publication in Cell.   

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Congratulations to Ceciel Jegers, Boehringer Ingelheim Fellowship winner!

Our PhD student Ceciel Jegers has just been awarded a Boehringer Ingelheim Fellowship to pursue her PhD studies on multi-enzyme condensates. Read more here. Way to go, Ceciel!

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Molecular biology: A liquid reservoir for silent chromatin

Tony and our postdoc Adam Klosin have written a Nature “News & Views” about chromatin compaction in liquid droplets based on two articles in the latest issue of Nature (Strom et al & Larson et al). Read the full News & Views piece here.   Klosin A, Hyman AA. Molecular biology: A liquid reservoir for silent chromatin. Nature […]

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The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin – congratulations to Jeff Woodruff and colleagues on their paper in Cell!

Our latest publication is out now in Cell! In this work, led by Jeff Woodruff, we used defined components to reconstitute a minimal centrosome in vitro that can nucleate microtubule asters.  Our results suggest that the centrosome acts a selective phase that nucleates microtubules by concentrating microtubule polymerases and soluble tubulin.     Read the full paper in Cell, and watch the video abstract […]

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Stem cells: the new “model organism”

In a new perspective published in Molecular Biology of the Cell, Tony Hyman and David Drubin “argue that combined advances in genome editing, stem cell production, and organoid derivation from stem cells represent a revolution in cell biology.”  These technological advances mean that stem cell studies could now replace molecular and cell biology studies traditionally […]

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  • Archives


  • Selected Essays

















  • Recent Videos


    An interview with Tony about Phase Transitions and Disease


    Phase separation in cell polarity: Saha et al, Cell 2016


    Encouraging Innovation, iBiology.org


    The genetics linking temperature and fertility in worms: Leaver et al, Biology Open 2016


    Cell PaperFlick on Phase Transitions in Disease


    Check out this playlist to watch all the videos in our "Two Minute Talk" Series


    Ways of Growing, a film created for the MitoSys Project


    What is a Discovery?


    Embryonic Development of C.elegans