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Karen Oegema

Karen Oegema
Professor of Cellular and Molecular Medicine, Univ. of California, San Diego

Hyman Lab postdoc from 1998-2001

Hyman Lab publications and collaborations:
Gonczy P, Echeverri C, Oegema K, Coulson A, Jones SJ, Copley RR, Duperon J, Oegema J, Brehm M, Cassin E, Hannak E, Kirkham M, Pichler S, Flohrs K, Goessen A, Leidel S, Alleaume AM, Martin C, Ozlu N, Bork P, Hyman AA. (2000) Functional genomic analysis of cell division in C.elegans using RNAi of genes on chromosome III. Nature 408(6810): 331-6.

Oegema K, Desai A, Rybina S, Kirkham M, Hyman AA. (2001) Functional analysis of kinetochore assembly in Caenorhabditis elegans. J Cell Biol 2001 153(6): 1209-26

Hannak E, Kirkham M, Hyman A A and Oegema K (2001) Aurora-A kinase is required for centrosome maturation in C. elegans. J Cell Biol 155(7): 1109-1115

Hannak E, Oegema K, Kirkham M, Gonczy P, Habermann B, Hyman AA (2002) The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent. J Cell Biol. 157(4): 591-602

Kirkham M, Mueller-Reichert T, Oegema K, Grill S, Hyman AA (2003) SAS-4 Is a C. elegans Centriolar Protein that Controls Centrosome Size. Cell. 112: 575-587

Desai A, Rybina S, Muller-Reichert T, Shevchenko A, Shevchenko A, Hyman A, Oegema K. (2003) KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans. Genes Dev. 17(19): 2421-35

Sonnichsen B, Koski LB, Walsh A, Marschall P, Neumann B, Brehm M, Alleaume AM, Artelt J, Bettencourt P, Cassin E, Hewitson M, Holz C, Khan M, Lazik S, Martin C, Nitzsche B, Ruer M, Stamford J, Winzi M, Heinkel R, Roder M, Finell J, Hantsch H, Jones SJ, Jones M, Piano F, Gunsalus KC, Oegema K, Gonczy P, Coulson A, Hyman AA, Echeverri CJ. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature. 434(7032): 462-9

Oegema K, Hyman AA. (2006) Cell division. WormBook. 1-40.

Sandall S, Severin F, McLeod IX, Yates JR 3rd, Oegema K, Hyman A, Desai A. (2006) A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension. Cell. 127(6): 1179-91.

Schlaitz AL, Srayko M, Dammermann A, Quintin S, Wielsch N, Macleod I, de Robillard Q, Zinke A, Yates JR 3rd, Muller-Reichert T, Shevchenko A, Oegema K, Hyman AA. (2007) The C. elegans RSA Complex Localizes Protein Phosphatase 2A to Centrosomes and Regulates Mitotic Spindle Assembly. Cell. 128(1): 115-27.

Green RA, Audhya A, Pozniakovsky A, Dammermann A, Pemble H, Monen J, Portier N, Hyman A, Desai A, Oegema K. (2008) Expression and Imaging of Fluorescent Proteins in the C. elegans Gonad and Early Embryo. Methods Cell Biol. 85: 179-218

Green, RA; Kao, HL; Audhya, A; Arur, S; Mayers, JR; Fridolfsson, HN; Schulman, M; Schloissnig, S; Niessen, S; Laband, K; Wang, SH; Starr, DA; Hyman, AA; Schedl, T; Desai, A; Piano, F; Gunsalus, KC; Oegema, K (2011). A High-Resolution C. elegans Essential Gene Network Based on Phenotypic Profiling of a Complex Tissue. Cell: 145(3): 470-482

Wuekese O, Bunkenborg J, Hein MY, Zinke A, Viscardi V, Woodruff JB, Oegema K, Mann M, Andersen JS, Hyman AA. (2014). The C. elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm prior to incorporation into the PCM matrix. Mol Biol Cell: pii: mbc.E13-09-0514.

Woodruff JB, Wueseke O, Viscardi V, Mahamid J, Ochoa SD, Bunkenborg J, Widlund PO, Pozniakovsky A, Zanin E, Bahmanyar S, Zinke A, Hong SH, Decker M, Baumeister W, Andersen JS, Oegema K, Hyman AA. (2015). Centrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitro. Science: 348(6236):808-12.

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