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Fedor Severin

Fedor Severin
Group Leader, A.N. Belozersky Institute of Physico Chemical Biology, MSU

Hyman Lab postdoc from 1993-2002

Hyman Lab publications and collaborations:
Sorger P.K. Severin F. and Hyman A.A. (1994) Factors required for kinetochore binding to microtubules in vitro J.Cell Biol. 127: (995-1008).

Blocker, A. Severin, F.F. Habermann, A. Hyman, A.A. Griffiths, G. and Burkhardt, J.K. (1996) MAP-dependent binding of phagosomes to microtubules. J. Biol. Chem 271: 3803-3811

Blocker, A. Severin, F.F Burkhardt, J.K. Hyman A.A. and Griffiths, G. (1997) Molecular requirements for Bi-directional movement of phagasomes along microtubules. J.Cell.Biol. 136: 1-17

Severin F, Sorger P.K. and Hyman A.A. (1997) Kinetochores distinguish between GTP and GDP forms of the microtubule lattice. Nature 388: 888-891

Mueller T. Chretien D, Severin F. and Hyman A.A. (1998) Structural changes at microtubule ends accompanying GTP hydrolysis: information from a slowly hydrolyzeable analogue of GTP, GMPCPP. PNAS 95: 3661-3666

Blocker A, Griffiths, G. Olivao JC, Hyman A.A and Severin F. (1998) A role for microtubule dynamics in phagasome movement. J Cell Sci 111: 303-312

Biggins, S., Severin, F.F., Bhalla, N., Sassoon, I., Hyman, A.A., Murray, A.W. (1999) The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast. Genes Dev 13(5): 532-44

Sassoon, I., Severin, F.F., Andrews, P.D., Taba, M.R., Kaplan, K.B., Ashford, A.J., Stark, M.J., Sorger, P.K., Hyman, A.A. (1999) Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p. Genes Dev 13(5): 545-55

Severin, F., Kaplan, K., Sorger, P. and Hyman, T. (1999) In vitro assays for studying Saccharomyces cerevisiae kinetochore activitiy. Methods in Cell Biology 61: 145-153

Nielsen, E., Severin, F., Backer, J.M., Hyman, A.A. and Zerial, M. (1999) Rab5 regulates motility of early endosomes on microtubules. Nature Cell Biology 6: 376-382

De Vos K, Severin F, Van Herreweghe F, Vancompernolle K, Goossens V, Hyman A, Grooten J. (2000) Tumor necrosis factor induces hyperphosphorylation of kinesin light chain and inhibits kinesin-mediated transport of mitochondria. Cell Biol. 149(6): 1207-14.

Nielsen E, Severin F, Hyman AA, Zerial M. (2001). In vitro reconstitution of endosome motility along microtubules. Methods Mol Biol 164:133-46

Severin F, Habermann B, Huffaker T and Hyman T. (2001) Stu2 Promotes Mitotic Spindle Elongation in Anaphase. J Cell Biol 2001 153(2): 435-442

Severin F, Hyman A A and Piatti S (2001) Correct spindle elongation at the metaphase/anaphase transition is an APC-dependent event in budding yeast. J Cell Biol 155(5): 711-717

Severin FF, Hyman AA (2002) Pheromone Induces Programmed Cell Death in S. cerevisiae. Curr Biol. 12(7): R233-5

Pozniakovsky AI, Knorre DA, Markova OV, Hyman AA, Skulachev VP, Severin FF. (2005) Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast. J Cell Biol. 168(2): 257-69

Sandall S, Severin F, McLeod IX, Yates JR 3rd, Oegema K, Hyman A, Desai A. (2006) A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension. Cell. 127(6): 1179-91.

Elie-Caille C, Severin F, Helenius J, Howard J, Muller DJ, Hyman AA. (2007) Straight GDP-tubulin protofilaments form in the presence of taxol. Curr Biol. 17(20): 1765-70.

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